Isosorbide mononitrate is used to prevent chest pain in patients with a certain heart condition (coronary artery disease).This medication belongs to a class of drugs known as nitrates. Accessed Sept. 7, 2022. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. May also be prescribed off label for Esophageal Spasm. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Heres what you need to know about alcohol and blood pressure including how alcohol can interact with your blood pressure medications. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). Isosorbide mononitrate (Monoket) is not known to affect the kidneys. It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle. Do not share this medication with others. Changing positions slowly can help lessen dizziness. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. Discuss the risks and benefits with your doctor. Daily headaches are a common side effect. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Longer-acting tablets and capsules are taken once daily in the morning. Isosorbide mononitrate (Monoket) can cause some serious health issues. My EKG showed Assess your symptoms online with our free symptom checker. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. information submitted for this request. A very serious allergic reaction to this drug is rare. . Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. The extended-release capsule usually is taken once daily. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. With any medication, there are risks and benefits. It does not have such side effects. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Normal ecg doesn't rule out heart disease. The table below contains some of the most common ones associated with isosorbide mononitrate. May also be prescribed off label for Esophageal Spasm. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. eCollection 2021. Methods: In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). tell your doctor and pharmacist if you are allergic to isosorbide; nitroglycerin tablets, patches, or ointment; any other medications, or any of the ingredients in isosorbide tablets, extended-release tablets, or extended-release capsules. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Accessed Sept. 7, 2022. It can cause your blood pressure to become dangerously low. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. official website and that any information you provide is encrypted Selected from data included with permission and copyrighted by First Databank, Inc. Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Drug interactions may change how your medications work or increase your risk for serious side effects. What conditions does Isosorbide Mononitrate treat? You need to take it every day in order for it to work. Some side effects may occur that usually do not need medical attention. Making any changes without doctor's advice can be dangerous. Consult your doctor before breast-feeding. Do not take more or less of it or take it more often than prescribed by your doctor. Do not take two doses together to make up for a missed dose. MeSH Herbal medications in cardiovascular medicine. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Last Revised - 09/15/2019. 46 ratings on Drugs.com. View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. from the best health experts in the business. . sharing sensitive information, make sure youre on a federal The tablet usually is taken two or three times daily. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. Advertising revenue supports our not-for-profit mission. 7 disease interactions. Sept. 26, 2022. Each day, take the first dose when you wake up, then take the second dose 7 hours later. You can consult me online for homeopathic treatment. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. Ask your pharmacist for a list of the ingredients. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. May also be prescribed off label for Esophageal Spasm. Otherwise, call a poison control center right away. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Isosorbide may cause other side effects. In: Current Medical Diagnosis & Treatment 2022. But only about 25% of people who take herbal supplements tell their health care providers. We comply with the HONcode standard for trustworthy health information. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. Patient is a UK registered trade mark. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. We study 23,548 Isosorbide mononitrate users. Using this medicine with any of the following medicines is not recommended. Accessed Sept. 7, 2022. It is in the nitrate class of drugs. Ask your doctor before using aspirin together with alcohol. This document does not contain all possible drug interactions. You may opt-out of email communications at any time by clicking on If you have recently had a head injury or a heart attack. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Methods: This site complies with the HONcode standard for trustworthy health information: verify here. The effects of this exposure on a nursing infant are unknown. If you have any problems with the way your liver works, or any problems with the way your kidneys work. Unless your doctor tells you otherwise, continue your normal diet. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. Should I avoid certain foods while taking Isosorbide Mononitrate? Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. include protected health information. information highlighted below and resubmit the form. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. The extended-release tablet usually is taken once daily in the morning. What are the side effects of Isosorbide Mononitrate ? Some don't work well with prescription medicines. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). Minimally clinically significant. Natural Medicines. Bauer B (expert opinion). Does Isosorbide Mononitrate interact with other drugs you are taking? Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Click here for an email preview. The information on this page is written and peer reviewed by qualified clinicians. It is important to take the drug at the same times each day. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Ginkgo. daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Treatment and prognosis of heart failure with preserved ejection . Generic alternatives may be available. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. https://naturalmedicines.therapeuticresearch.com. Prescription and OTC In case of overdose, call the poison control helpline at 1-800-222-1222. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Do not double the dose to catch up. Along with its needed effects, a medicine may cause some unwanted effects. We don't support your browser. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Registered in England and Wales. This makes it easier for your heart to pump, relieving heart-related chest pain. Coenzyme Q-10 Natural Medicines. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. You may report side effects to the FDA at 1-800-FDA-1088. See also: aspirin side effects in more detail. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you may be dehydrated, if you have recently had a heart attack, or if you have or have ever had heart failure, low blood pressure, or hypertrophic cardiomyopathy (thickening of the heart muscles). Results: Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Things to remember when you fill your prescription. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. See the full pregnancy warnings document. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. All rights reserved. Drug information provided by: IBM Micromedex. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. https://naturalmedicines.therapeuticresearch.com. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . Try our Symptom Checker Got any other symptoms? Talk to your provider if you notice your chest pain starts to get worse. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Seek alternatives to the CYP3A4 substrate when possible. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Disclaimer. Does Viagra add to the risks of melanoma? If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Never take extra doses or stop taking it suddenly unless your provider tells you to do so. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Headache is often a sign that this medication is working. Even if the medication is working, you may experience some unwanted side effects. All rights reserved. Isosorbide mononitrate has an average rating of Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Accessed Sept. 7, 2022. You can take your doses either before or after meals. St. Joseph 81 mg Aspirin Enteric Safety-Coated. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Accessed Sept. 7, 2022. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. Moderately clinically significant. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. Avoid combinations; the risk of the interaction outweighs the benefit. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Tachjian A, et al. Thirty percent of the patients never experienced headache from the given dosages. privacy practices. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. What are the interactions of Isosorbide Mononitrate ? To use the sharing features on this page, please enable JavaScript. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Journals of the American College of Cardiology. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. https://www.uptodate.com/contents/search. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. Can isosorbide mononitrate cause problems? This medicine is available only with your doctor's prescription. Consult your doctor for more details. Review/update the Tolerance is more likely to happen if you don't take your dose at the same time every day. View more. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Do not keep out-of-date or unwanted medicines. 1998 Oct;61(10):577-83. Then, there was a two-week placebo washout, after which the alternative treatment was given. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. It is not intended as medical advice for individual conditions or treatment. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Information is also available online at https://www.poisonhelp.org/help. FOIA Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Higher dosages are associated with stomach irritation and What should I know about storage and disposal of this medication? Some of these interactions can be life-threatening. Change positions slowly until your body is used to the medication. Aspirin relieves pain and inflammation and helps to thin the blood. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . This branded product is no longer on the market. This content does not have an Arabic version. Overview of herbal medicines and dietary supplements. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. Consult your pharmacist or local waste disposal company. Natural Medicines. Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller.